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/ Departments and outpatient clinics / Oncological and Radiological Centre Pardubice

Oncological and Radiological Centre Pardubice

The Comprehensive Cancer Centre of the Pardubice Region provides treatment for most forms of malignant neoplasms, thanks to the expertise and experience of our specialists and modern equipment.

Multiscan began operating in the Pardubice hospital in mid-2002 and provides care for patients of the Pardubice Region in the field of clinical and radiation oncology. In accordance with the concept of oncological care in the Pardubice Region, in 2005 Multiscan secured the operation of a clinical oncology outpatient clinic in Svitavy and in 2006 took over oncology outpatient clinics in Chrudim and Ústí nad Orlicí.

On the initiative and with funding from Multiscan, a modern inpatient section was built at the Pardubice Regional Hospital. In the middle of 2009, in an effort to continuously improve the quality of care provided, the Department of Central Preparation of Cytostatics of the subsidiary Multiscan Pharma s.r.o. started its operation. In this department, medicines are prepared for cancer patients under strict hygiene and safety measures for all Multiscan clinical oncology outpatient clinics in the region and inpatient wards of the Pardubice Region Hospital.

In 2010, with the support of EU funding, the instrumentation of the Multiscan Oncology Centre was significantly upgraded. Specifically, it is a state-of-the-art computed tomograph with a wide imaging field, essential for radiation oncology, and a new magnetic resonance imaging machine. Another heavy linear accelerator from Varian, equipped with the RapidArc beam intensity modulated radiotherapy technique and image-guided radiotherapy system, completed the technical equipment of the centre.

In 2015, another significant upgrade of the equipment was made with EU funds by purchasing a new generation Varian TrueBeam linear accelerator, allowing, in addition to the already mentioned possibilities, high-precision high-dose stereotactic irradiation of lesions.

doc. MUDr. Jaroslav Vaňásek, CSc.

/ Chief Physician Emeritus

Work experience

1978 - 1987 FN Hradec Králové - Department of Radiotherapy, Radiology Clinic - physician
1987 - 1999 Assistant Professor at the Department of Radiology and Nuclear Medicine (1996 - 1999 as Head of the Department of Oncology and Radiotherapy)
1999 - present Department of Clinical and Radiation Oncology, Comprehensive Cancer Centre of the Pardubice Region, Multiscan, s.r.o. and Hospital of the Pardubice Region, a.s., Pardubice Hospital, - physician (i.e. as chief physician of the department and head of the Comprehensive Cancer Centre of the Pardubice Region, Multiscan, s.r.o.)

Education

1972 - 1978 Faculty of Medicine, Charles University in Hradec Kralove, major - general medicine
1982 1st degree certification in radiotherapy
1986 2nd degree certification in radiotherapy
1992 Candidate of Medical Sciences in Radiology and Radiology, 1st Faculty of Medicine, Charles University in Prague
2001 appointment as Associate Professor, Military Medical Academy J.E.Purkyně, Hradec Králové, field of military radiobiology

Publication activity in the last 5 years

Scientific monographs and chapters in monographs

Vaňásek, J; Odrážka, K.; Doležel, M.; Šefrová, J. Radiotherapy. In: Kolombo I, Hanuš T, Odrážka K, editors. Renal cell carcinoma. Prague: Mladá fronta; 2010. p. 179-188. ISBN 978-80-204-2344-3.

Odrážka, K.; Vaňásek, J. ; Šefrová, J.; Doležel, M. Systemic therapy. In: Kolombo I, Hanuš T, Odrážka K, editors. Carcinoma of the kidney. Prague: Mladá fronta; 2010. p. 150-173. ISBN 978-80-204-2344-3.

Kolářová, I.; Vaňásek, J. ; Odrážka, K.; Petruželka, L.; Doležel, M.; Nechvíl, K. The use of PET/CT scanning in planning radiotherapy of ENT tumours . Nucleus HK, 2011. ISBN 978-80-87009-78-9.

Vaňásek J; Čermáková K; Kolářová I. Palliative care in oncology. University of Pardubice, Faculty of Health Studies, 2013. ISBN 978-80-7395-586-I.

Vaňásek J, Čermáková K, Kolářová I. Pain in nursing, University of Pardubice, Faculty of Health Sciences, 2014, ISBN 978-80-7395-769-8.

Original papers and review articles

Odrazka K, Dolezel M, Vanasek J , Vaculikova M, Zouhar M, Sefrova J, Paluska P, Vosmik M, Kohlova T, Kolarova I, Macingova Z, Navratil P, Brodak M, Prosvic P. Time course of late rectal toxicity after radiation therapy for prostate cancer. Prostate Cancer Prostatic Dis. 2010; 13:138 - 43 ISSN 1365-7852 [IF 2.096] (2009)

Dolezel M, Odrazka K, Vaculikova M, Vanasek J, Sefrova J, Paluska P, Zouhar M, Jansa J, Macingova Z, Jarosova L, Brodak M, Moravek P, Hartmann I. Dose escalation in prostate radiotherapy up to 82 Gy using simultaneous integrated boost. Strahlenther. Onkol. 2010; 186:197 - 202 ISSN 0179-7158 [IF 3.776] (2009)

Odrazka K, Dolezel M, Vanasek J , Vaculikova M, Zouhar M, Sefrova J, Paluska P, Vosmik M, Kohlova T, Kolarova I, Navratil P, Brodak M, Prosvic P, Hoffmann P. Late toxicity after conformal and intensity-modulated radiation therapy for prostate cancer: impact of previous surgery for benign prostatic hyperplasia. 2010;17: 784-790. Int J Urol. 2010 Sep ;17(9):784-90. Epub 2010 Jul 6 ISSN 1442-2042 [IF 1,158].

Kolářová I, Vaňásek J: Adjuvant hormonal treatment of breast cancer in postmenopausal women. Remedia 2011, vol. 21, no. 6, pp. 456-461. ISSN: 0862-8947; 2336-3541.

Dolezel M, Odrazka K, Vanasek J , Kohlova T, Kroulik T, Kudelka K, Spitzer D, Mrklovsky M, Tichy M, Zizka J, Jalcova L. MRI-based preplanning in patients with cervical cancer treated with 3D brachytherapy. Br J Radiol. 2011 Sep;84(1005):850-6. [IF=2,062]

Kolarova I, Vanasek J, Kandrnal V, Odrazka K, Dusek L, Chrobok V, Belohlavek O, Dolezel M, Petruzelka L, Michalek R, Jarkovsky J.: PET/CT significance for planning radiotherapy of head and neck cancer. Neoplasma. 2012;59(5):536-40 [IF=1.574]

Doležel, M.; Vaňásek, J. ; Odrážka, K.; Kroulík, T.; Kudelka, K.; Tichý, M.; Košt'ál, M.; Vocásek, Z. [3D MRI-based brachytherapy in patients with locally advanced cervical carcinoma - early clinical results]. Ceska Gynekol. 2012 Dec;77(6):507-13.

Dolezel M, Odrazka K, Zizka J, Vanasek J, Kohlova T, Kroulik T, Spitzer D, Ryska P, Tichy M, Kostal M, Jalcova L. MRI-based preplanning using CT and MRI data fusion in patients with cervical cancer treated with 3D-based brachytherapy: feasibility and accuracy study. Int J Radiat Oncol Biol Phys 2012 Jan 31. [Epub ahead of print] [IF=4,502]

Dolezel M, Stastny K, Odrazka K, Vanasek J, Kohlova T, Dvorakova D, Kolarova I, Kroulik T, Jalcova L.: Perioperative interstitial CT-based brachytherapy boost in breast cancer patients with breast conservation after neoadjuvant chemotherapy. Neoplasma. 2012;59(5):494-9. doi: 10.4149/neo_2012_063. [IF=1.574]

Dolezel M, Odrazka K, Vanasek J , Vaculikova M, Sefrova J, Jansa J, Macingova Z, Brodak M, Hartmann I, Melichar B. Neoadjuvant hormonal therapy in prostate cancer - impact of PSA level before radiotherapy. JBUON 2013;18(4):949-953. [IF=0.701]

Dolezel, M.; Odrazka, K.; Vanasek, J.; Vaculikova, M.; Shefrova, J.; Jansa, J.; Macingova, Z.; Zouhar, M.; Paluska, P.; Brodak, M.; Hartmann, I. Five-year outcomes of IMRT for prostate cancer - toxicity. Clinical Oncology 2013;26(6):409-14.

Odrážka, K.; Doležel, M.; Vaňásek, J, Vaculíková, M.; Zouhar, M.; Šefrova, J.; Paluska, P.; Vošmik, M.; Kohlová, T.; Kolářová, I.; Brodák, M.; Navrátil, P.; Prošvic, P.; Hoffmann, P.; Hafuda, A. Five-year results of IMRT for prostate cancer - tumor control. Clinical Oncology. 2013;26:415-420 ISSN 0862-495X.

Vanasek J., Odrazka K., Dusek L., Jarkovsky J., Michalek R., Chrobok V., Dolezel M., Kolarova I.: Experience with intensity-modulated radiotherapy in the treatment of head and neck cancer. JBUON, 2013; 18/4): 970-976. ISSN: 1107-0625, online ISSN: 2241-6293.[IF=0.701]

Vanasek J , Odrazka K, Dolezel M, Kolarova I, et al. Statistical Analysis of Dose-Volume Profiles and its Implication for Radiation Therapy Planning in Prostate Carcinoma. Int J Radiat Oncol Biol Phys. 2013 Apr 26. pii: S0360-3016(13)00329, [IF=4,502]

Doležel M, Odrážka K, Vaňásek J, Mrklovský M, Hoffmann P, Lucký K, Hartmann I: Dose escalation to intraprostatic lesions - results of acute and early chronic toxicity. Ces Urol 2013;17(3):175-182.

Vanasek J, Odrazka K, Dolezel M, Dusek L, Jarkovsky J, Hlavka A, Valentova E, Kolarova I: Searching for appropriate IGRT method in prostate cancer - implications for safety margin. Tumors 2014, 100: 518-523. [IF=1,269]

Kolarova I, Vaňásek J: Treatment of bone metastases. Postgraduate Medicine, Clinical Oncology 2014; volume 16, number 3, pages 323-328, ISSN 1212-4184.

Vanasek J, Odrazka K, Dolezel M, Dusek L, Jarkovsky J, Hlavka A, Valentova E, Kolarova I. Searching for an appropriate image-guided radiotherapy method in prostate cancer--implications for safety margin.Tumors 2014;100:518-523. IF 1.090.

Kolarova I, Vaňásek J: Treatment of patients with central nervous system involvement in HER2-positive breast cancer in the context of the first ASCO guidelines 2014. Oncology 2015; 9(3): 151-154.

Dolezel M, Slezak P, Odrazka K, Vanasek J, Hlavka A, Ulrych V, Stuk J, Waczulikova, Hartmann I: Interfraction variation in prostate cancer - analysis of 11726 cone-beam CT. JBUON 2015; 20(4): 1081-1087. ISSN: 1107-0625, online ISSN: 2241-6293. [IF=0.741]